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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP45
All Species:
24.24
Human Site:
Y666
Identified Species:
41.03
UniProt:
Q70EL2
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q70EL2
NP_001073950
814
91733
Y666
E
K
K
V
E
G
V
Y
T
N
A
R
K
Q
L
Chimpanzee
Pan troglodytes
XP_001139771
814
91702
Y666
E
K
K
V
E
G
V
Y
T
N
A
R
K
Q
L
Rhesus Macaque
Macaca mulatta
XP_001085248
815
91829
Y667
E
K
K
V
E
G
V
Y
T
N
A
R
K
Q
L
Dog
Lupus familis
XP_539054
796
87704
I657
N
A
R
K
Q
L
L
I
S
A
V
P
A
I
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8K387
813
90343
Y665
E
K
K
A
G
G
V
Y
T
N
A
R
K
Q
L
Rat
Rattus norvegicus
Q2KJ09
826
93743
Y679
K
G
E
R
K
H
V
Y
T
N
A
K
K
Q
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506389
799
87920
I660
N
A
R
K
Q
L
L
I
S
V
V
P
A
V
L
Chicken
Gallus gallus
O57429
357
40913
V219
R
L
F
T
K
E
D
V
L
D
G
D
E
K
P
Frog
Xenopus laevis
Q6PAW2
901
101274
Y754
K
G
E
K
K
F
V
Y
T
N
A
K
K
Q
M
Zebra Danio
Brachydanio rerio
A8HAL1
815
90431
Q677
V
Y
R
D
A
L
K
Q
M
L
I
S
D
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121285
844
94413
C680
K
Q
N
C
K
M
V
C
T
P
S
T
K
Q
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790411
1122
123641
Y897
E
G
K
E
R
V
K
Y
T
D
A
S
K
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FPT5
1083
120752
P770
E
R
P
V
F
G
P
P
S
K
A
K
V
S
E
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
Y334
E
Q
L
K
D
F
N
Y
H
C
G
E
C
N
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.4
72.2
N.A.
77.4
38.7
N.A.
63.7
20.1
38.5
38
N.A.
N.A.
29.3
N.A.
29.9
Protein Similarity:
100
99.7
96.6
81.5
N.A.
85.3
59.6
N.A.
75.5
29.7
56.4
56.6
N.A.
N.A.
49.1
N.A.
45.3
P-Site Identity:
100
100
100
6.6
N.A.
86.6
46.6
N.A.
6.6
0
46.6
0
N.A.
N.A.
26.6
N.A.
53.3
P-Site Similarity:
100
100
100
33.3
N.A.
86.6
80
N.A.
33.3
26.6
80
6.6
N.A.
N.A.
53.3
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.6
35.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
8
8
0
0
0
0
8
58
0
15
0
0
% A
% Cys:
0
0
0
8
0
0
0
8
0
8
0
0
8
0
0
% C
% Asp:
0
0
0
8
8
0
8
0
0
15
0
8
8
0
0
% D
% Glu:
50
0
15
8
22
8
0
0
0
0
0
8
8
0
8
% E
% Phe:
0
0
8
0
8
15
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
22
0
0
8
36
0
0
0
0
15
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
15
0
0
8
0
0
8
0
% I
% Lys:
22
29
36
29
29
0
15
0
0
8
0
22
58
8
0
% K
% Leu:
0
8
8
0
0
22
15
0
8
8
0
0
0
0
50
% L
% Met:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
15
% M
% Asn:
15
0
8
0
0
0
8
0
0
43
0
0
0
8
0
% N
% Pro:
0
0
8
0
0
0
8
8
0
8
0
15
0
8
15
% P
% Gln:
0
15
0
0
15
0
0
8
0
0
0
0
0
58
0
% Q
% Arg:
8
8
22
8
8
0
0
0
0
0
0
29
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
22
0
8
15
0
8
8
% S
% Thr:
0
0
0
8
0
0
0
0
58
0
0
8
0
0
0
% T
% Val:
8
0
0
29
0
8
50
8
0
8
15
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
58
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _